Targeting PPAR-γ to design and synthesize antidiabetic thiazolidines

A series of thiazolidine derivatives were designed by docking into PPAR-γ active site. The structure of target was obtained from the protein data bank (PDB ID P37231). A library of 200 molecules was prepared on random basis. Molecular docking studies were performed using VLife MDS 4.3 software. Afte...

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Detalles Bibliográficos
Autores principales: Sawant, Ramesh L., Wadekar, Jyoti B., Kharat, Santosh B., Makasare, Hitakshi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088216/
https://www.ncbi.nlm.nih.gov/pubmed/30108464
http://dx.doi.org/10.17179/excli2018-1325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088216/
https://www.ncbi.nlm.nih.gov/pubmed/30108464
http://dx.doi.org/10.17179/excli2018-1325

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