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Antiepileptic Drugs Elevate Astrocytic Kir4.1 Expression in the Rat Limbic Region

Inwardly rectifying potassium (Kir) channel subunits Kir4.1 are specifically expressed in astrocytes and regulate neuronal excitability by mediating spatial potassium buffering. In addition, it is now known that astrocytic Kir4.1 channels are closely involved in the pathogenesis of epilepsy. Here, t...

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Detalles Bibliográficos
Autores principales: Mukai, Takahiro, Kinboshi, Masato, Nagao, Yuki, Shimizu, Saki, Ono, Asuka, Sakagami, Yoshihisa, Okuda, Aoi, Fujimoto, Megumi, Ito, Hidefumi, Ikeda, Akio, Ohno, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088221/
https://www.ncbi.nlm.nih.gov/pubmed/30127740
http://dx.doi.org/10.3389/fphar.2018.00845