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S100A4(+) Macrophages Are Necessary for Pulmonary Fibrosis by Activating Lung Fibroblasts

S100A4, a calcium-binding protein, can promote pulmonary fibrosis via fibroblast activation. Due partly to its various cellular origins, the exact role of S100A4 in the development of lung fibrosis remains elusive. Here, we show that in the bronchoalveolar lavage fluid, numbers of S100A4(+) macropha...

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Detalles Bibliográficos
Autores principales: Li, Yanan, Bao, Jing, Bian, Yangyang, Erben, Ulrike, Wang, Peigang, Song, Kun, Liu, Shuangqing, Li, Zhenzhen, Gao, Zhancheng, Qin, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088238/
https://www.ncbi.nlm.nih.gov/pubmed/30127784
http://dx.doi.org/10.3389/fimmu.2018.01776