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Porcine Fetal-Derived Fibroblasts Alter Gene Expression and Mitochondria to Compensate for Hypoxic Stress During Culture

The Warburg effect is characterized by decreased mitochondrial oxidative phosphorylation and increased glycolytic flux in adequate oxygen. The preimplantation embryo has been described to have characteristics of the Warburg effect, including similar changes in gene expression and mitochondria, which...

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Detalles Bibliográficos
Autores principales: Mordhorst, Bethany R., Murphy, Stephanie L., Schauflinger, Martin, Rojas Salazar, Shirley, Ji, Tieming, Behura, Susanta K., Wells, Kevin D., Green, Jonathan A., Prather, Randall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088251/
https://www.ncbi.nlm.nih.gov/pubmed/30089028
http://dx.doi.org/10.1089/cell.2018.0008