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Porcine Fetal-Derived Fibroblasts Alter Gene Expression and Mitochondria to Compensate for Hypoxic Stress During Culture
The Warburg effect is characterized by decreased mitochondrial oxidative phosphorylation and increased glycolytic flux in adequate oxygen. The preimplantation embryo has been described to have characteristics of the Warburg effect, including similar changes in gene expression and mitochondria, which...
Autores principales: | Mordhorst, Bethany R., Murphy, Stephanie L., Schauflinger, Martin, Rojas Salazar, Shirley, Ji, Tieming, Behura, Susanta K., Wells, Kevin D., Green, Jonathan A., Prather, Randall S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088251/ https://www.ncbi.nlm.nih.gov/pubmed/30089028 http://dx.doi.org/10.1089/cell.2018.0008 |
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