Altered Trek-1 Function in Sortilin Deficient Mice Results in Decreased Depressive-Like Behavior

The background potassium channel TREK-1 has been shown to be a potent target for depression treatment. Indeed, deletion of this channel in mice resulted in a depression resistant phenotype. The association of TREK-1 with the sorting protein sortilin prompted us to investigate the behavior of mice de...

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Detalles Bibliográficos
Autores principales: Moreno, Sébastien, Devader, Christelle M., Pietri, Mariel, Borsotto, Marc, Heurteaux, Catherine, Mazella, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088259/
https://www.ncbi.nlm.nih.gov/pubmed/30127743
http://dx.doi.org/10.3389/fphar.2018.00863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088259/
https://www.ncbi.nlm.nih.gov/pubmed/30127743
http://dx.doi.org/10.3389/fphar.2018.00863

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