Novel Quantitative Analyses of Spontaneous Synaptic Events in Cortical Pyramidal Cells Reveal Subtle Parvalbumin-Expressing Interneuron Dysfunction in a Knock-In Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder that has become a compelling global public health concern. Besides pathological hallmarks such as extracellular amyloid plaques, intracellular neurofibrillary tangles (NFTs), and loss of neurons and synapses, clinical reports have shown that e...

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Detalles Bibliográficos
Autores principales: Chen, Lingxuan, Saito, Takashi, Saido, Takaomi C., Mody, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Confirmation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088364/
https://www.ncbi.nlm.nih.gov/pubmed/30105300
http://dx.doi.org/10.1523/ENEURO.0059-18.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088364/
https://www.ncbi.nlm.nih.gov/pubmed/30105300
http://dx.doi.org/10.1523/ENEURO.0059-18.2018

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