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Rapid access to RNA resonances by proton-detected solid-state NMR at >100 kHz MAS

Fast (>100 kHz) magic angle spinning solid-state NMR allows combining high-sensitive proton detection with the absence of an intrinsic molecular weight limit. Using this technique we observe for the first time narrow (1)H RNA resonances and assign nucleotide spin systems with only 200 μg of unifo...

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Detalles Bibliográficos
Autores principales: Marchanka, Alexander, Stanek, Jan, Pintacuda, Guido, Carlomagno, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088370/
https://www.ncbi.nlm.nih.gov/pubmed/29974085
http://dx.doi.org/10.1039/c8cc04437f