Optical molecular imaging of lysyl oxidase activity – detection of active fibrogenesis in human lung tissue

Aberrant fibrogenesis is a feature of many diseases in multiple organ systems. The lysyl oxidase family of enzymes are central to tissue homeostasis and elevated lysyl oxidase activity is implicated in fibroproliferation as well as in cancer stroma. We have synthesised a novel fluorogenic reporter f...

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Detalles Bibliográficos
Autores principales: Aslam, Tashfeen, Miele, Amy, Chankeshwara, Sunay V., Megia-Fernandez, Alicia, Michels, Chesney, Akram, Ahsan R., McDonald, Neil, Hirani, Nik, Haslett, Chris, Bradley, Mark, Dhaliwal, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088439/
https://www.ncbi.nlm.nih.gov/pubmed/30155003
http://dx.doi.org/10.1039/c5sc01258a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088439/
https://www.ncbi.nlm.nih.gov/pubmed/30155003
http://dx.doi.org/10.1039/c5sc01258a

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