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Assessment of Toxicity and Absorption of the Novel AA Derivative AA-Pme in SGC7901 Cancer Cells In Vitro and in Zebrafish In Vivo

BACKGROUND: Asiatic acid (AA; 2α,3β,23-trihydroxyurs-12-ene-28-oic acid) is an active compound derived from Centella asiatica, a traditional medicinal plant used widely in many Asian countries, particularly for the treatment of cancer. However, the modified AA derivative N-(2α,3β,23-acetoxyurs-12-en...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Xiao, Qi, Wu, Wenxiu, Wu, Yao, Wei, Yingjie, Jing, Yue, Gong, Zhunan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088512/
https://www.ncbi.nlm.nih.gov/pubmed/30076700
http://dx.doi.org/10.12659/MSM.909606