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Complete inhibition of phosphatase and tensin homolog promotes the normal and oxygen-glucose deprivation/reperfusion-injured PC12 cells to cell death

Introduction: Lipid phosphatase and tensin homolog deleted from chromosome 10 (PTEN) antagonizes phosphoinositide 3-kinase (PI3K)/AKT cell survival pathway. The effect of PTEN inhibitors has been rarely examined on cell survival following reperfusion injury. In this study, we investigated the neurop...

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Detalles Bibliográficos
Autores principales: Minaei Beyrami, Sohrab, Khadem Ansari, Mohammad Hasan, Rasemi, Yousef, Shakib, Nader, Karimi, Pouran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088763/
https://www.ncbi.nlm.nih.gov/pubmed/30116506
http://dx.doi.org/10.15171/jcvtr.2018.13