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Iron overloaded polarizes macrophage to proinflammation phenotype through ROS/acetyl‐p53 pathway
PURPOSE: Macrophages play critical roles in inflammation and wound healing and can be divided into two subtypes: classically activated (M1) and alternatively activated (M2) macrophages. Macrophages also play important roles in regulating iron homeostasis, and intracellular iron accumulation induces...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089144/ https://www.ncbi.nlm.nih.gov/pubmed/29989329 http://dx.doi.org/10.1002/cam4.1670 |