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Iron overloaded polarizes macrophage to proinflammation phenotype through ROS/acetyl‐p53 pathway

PURPOSE: Macrophages play critical roles in inflammation and wound healing and can be divided into two subtypes: classically activated (M1) and alternatively activated (M2) macrophages. Macrophages also play important roles in regulating iron homeostasis, and intracellular iron accumulation induces...

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Detalles Bibliográficos
Autores principales: Zhou, Yun, Que, Ke‐Ting, Zhang, Zhen, Yi, Zu J., Zhao, Ping X., You, Yu, Gong, Jian‐Ping, Liu, Zuo‐Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089144/
https://www.ncbi.nlm.nih.gov/pubmed/29989329
http://dx.doi.org/10.1002/cam4.1670