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A regulatory mutant on TRIM26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response

The major histocompatibility complex (MHC) is most closely associated with nasopharyngeal carcinoma (NPC), but the complexity of its genome structure has proven challenging for the discovery of causal MHC loci or genes. We conducted a targeted MHC sequencing in 40 Cantonese NPC patients followed by...

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Detalles Bibliográficos
Autores principales: Lyu, Xiao‐Ming, Zhu, Xiao‐Wei, Zhao, Manli, Zuo, Xian‐Bo, Huang, Zhong‐Xi, Liu, Xiao, Jiang, Tao, Yang, Xue‐Xi, Li, Xin, Long, Xiao‐Bing, Wang, Jian‐Guo, Li, Jin‐Bang, Han, Ming‐Yu, Wang, Shuang, Liu, Teng‐Fei, Zhang, Bo, Sun, Tao, Cheng, Zhi, Qiu, Mo‐Chang, Dong, Lei, Zheng, Lu, Zhang, Long‐Cheng, Wang, Jia‐Hong, Wei, Gan‐Guan, Yao, Kaitai, Wang, Qian, Zheng, Hou‐Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089173/
https://www.ncbi.nlm.nih.gov/pubmed/29956500
http://dx.doi.org/10.1002/cam4.1537