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Corticostriatal Transmission Is Selectively Enhanced in Striatonigral Neurons with Postnatal Loss of Tsc1

mTORC1 is a central signaling hub that integrates intra- and extracellular signals to regulate a variety of cellular metabolic processes. Mutations in regulators of mTORC1 lead to neurodevelopmental disorders associated with autism, which is characterized by repetitive, inflexible behaviors. These b...

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Detalles Bibliográficos
Autores principales: Benthall, Katelyn N., Ong, Stacie L., Bateup, Helen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089242/
https://www.ncbi.nlm.nih.gov/pubmed/29898392
http://dx.doi.org/10.1016/j.celrep.2018.05.037