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Role of Cytokine Combinations on CD4+ T Cell Differentiation, Partial Polarization, and Plasticity: Continuous Network Modeling Approach

Purpose: We put forward a theoretical and dynamical approach for the semi-quantitative analysis of CD4+ T cell differentiation, the process by which cells with different functions are derived from activated CD4(+) T naïve lymphocytes in the presence of particular cytokine microenvironments. We explo...

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Detalles Bibliográficos
Autores principales: Martinez-Sanchez, Mariana E., Huerta, Leonor, Alvarez-Buylla, Elena R., Villarreal Luján, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089340/
https://www.ncbi.nlm.nih.gov/pubmed/30127748
http://dx.doi.org/10.3389/fphys.2018.00877