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Applied diagnostics in liver cancer. Efficient combinations of sorafenib with targeted inhibitors blocking AKT/mTOR

Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related deaths worldwide. There is increasing interest in developing specific markers to serve as predictors of response to sorafenib and to guide targeted therapy. Using a sequencing platform designed to study somatic mutations...

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Detalles Bibliográficos
Autores principales: Llerena, Susana, García-Díaz, Nuria, Curiel-Olmo, Soraya, Agraz-Doblas, Antonio, García-Blanco, Agustín, Pisonero, Helena, Varela, María, Santibáñez, Miguel, Almaraz, Carmen, Cereceda, Laura, Martínez, Nerea, Arias-Loste, María Teresa, Puente, Ángela, Martín-Ramos, Luis, de Lope, Carlos Rodríguez, Castillo-Suescun, Federico, Cagigas-Fernandez, Carmen, Isidro, Pablo, Lopez-López, Carlos, Lopez-Hoyos, Marcos, Llorca, Javier, Agüero, Jesús, Crespo-Facorro, Benedicto, Varela, Ignacio, Piris, Miguel Ángel, Crespo, Javier, Vaqué, José Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089396/
https://www.ncbi.nlm.nih.gov/pubmed/30112114
http://dx.doi.org/10.18632/oncotarget.25766