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Chloroquine plays a cell-dependent role in the response to treatment of pancreatic adenocarcinoma

In this study, our aim is to assess the role played by autophagy and its inhibition in the different PDAC cellular compartments, and its involvement in chemo-resistance using primary human pancreatic cancer-derived cells (PCC) and Cancer Associated Fibroblasts (CAF). Autophagy flux, as measured by L...

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Detalles Bibliográficos
Autores principales: Molejon, María Inés, Swayden, Mirna, Fanale, Daniele, Bintz, Jennifer, Gayet, Odile, Soubeyran, Philippe, Iovanna, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089401/
https://www.ncbi.nlm.nih.gov/pubmed/30112111
http://dx.doi.org/10.18632/oncotarget.25745