Overlapping open reading frames strongly reduce human and yeast STN1 gene expression and affect telomere function

The levels of telomeric proteins, such as telomerase, can have profound effects on telomere function, cell division and human disease. Here we demonstrate how levels of Stn1, a component of the conserved telomere capping CST (Cdc13, Stn1, Ten1) complex, are tightly regulated by an upstream overlappi...

Descripción completa

Detalles Bibliográficos
Autores principales: Torrance, Victoria, Lydall, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089452/
https://www.ncbi.nlm.nih.gov/pubmed/30067734
http://dx.doi.org/10.1371/journal.pgen.1007523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089452/
https://www.ncbi.nlm.nih.gov/pubmed/30067734
http://dx.doi.org/10.1371/journal.pgen.1007523

Ejemplares similares