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Spatial and temporal proteome dynamics of glioma cells during oncolytic adenovirus Delta-24-RGD infection

Glioblastoma multiforme (GBM) is the most common and aggressive type of malignant glioma. Oncolytic adenoviruses are being modified to exploit the aberrant expression of proteins in tumor cells to increase the antiglioma efficacy. E1A mutant adenovirus Delta-24-RGD (DNX-2401) has shown a favorable t...

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Detalles Bibliográficos
Autores principales: González-Morales, Andrea, Zabaleta, Aintzane, Guruceaga, Elizabeth, Alonso, Marta M., García-Moure, Marc, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089549/
https://www.ncbi.nlm.nih.gov/pubmed/30123426
http://dx.doi.org/10.18632/oncotarget.25774