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Stim and Orai mediate constitutive Ca(2+) entry and control endoplasmic reticulum Ca(2+) refilling in primary cultures of colorectal carcinoma cells
Store-operated Ca(2+) entry (SOCE) provides a major Ca(2+) entry route in cancer cells. SOCE is mediated by the assembly of Stim and Orai proteins at endoplasmic reticulum (ER)-plasma membrane junctions upon depletion of the ER Ca(2+) store. Additionally, Stim and Orai proteins underpin constitutive...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089563/ https://www.ncbi.nlm.nih.gov/pubmed/30123430 http://dx.doi.org/10.18632/oncotarget.25785 |