Developmentally regulated H2Av buffering via dynamic sequestration to lipid droplets in Drosophila embryos

Regulating nuclear histone balance is essential for survival, yet in early Drosophila melanogaster embryos many regulatory strategies employed in somatic cells are unavailable. Previous work had suggested that lipid droplets (LDs) buffer nuclear accumulation of the histone variant H2Av. Here, we elu...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Matthew Richard, Stephenson, Roxan Amanda, Ghaemmaghami, Sina, Welte, Michael Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089599/
https://www.ncbi.nlm.nih.gov/pubmed/30044219
http://dx.doi.org/10.7554/eLife.36021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089599/
https://www.ncbi.nlm.nih.gov/pubmed/30044219
http://dx.doi.org/10.7554/eLife.36021

Ejemplares similares