Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

Proper kinetochore-microtubule attachments, mediated by the NDC80 complex, are required for error-free chromosome segregation. Erroneous attachments are corrected by the tension dependence of kinetochore-microtubule interactions. Here, we present a method, based on fluorescence lifetime imaging micr...

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Detalles Bibliográficos
Autores principales: Yoo, Tae Yeon, Choi, Jeong-Mo, Conway, William, Yu, Che-Hang, Pappu, Rohit V, Needleman, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089600/
https://www.ncbi.nlm.nih.gov/pubmed/30044223
http://dx.doi.org/10.7554/eLife.36392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089600/
https://www.ncbi.nlm.nih.gov/pubmed/30044223
http://dx.doi.org/10.7554/eLife.36392

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