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Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

Proper kinetochore-microtubule attachments, mediated by the NDC80 complex, are required for error-free chromosome segregation. Erroneous attachments are corrected by the tension dependence of kinetochore-microtubule interactions. Here, we present a method, based on fluorescence lifetime imaging micr...

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Detalles Bibliográficos
Autores principales:	Yoo, Tae Yeon, Choi, Jeong-Mo, Conway, William, Yu, Che-Hang, Pappu, Rohit V, Needleman, Daniel J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089600/ https://www.ncbi.nlm.nih.gov/pubmed/30044223 http://dx.doi.org/10.7554/eLife.36392

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