Impaired transmissibility of atypical prions from genetic CJD(G114V)

OBJECTIVE: To describe the clinicopathologic, molecular, and transmissible characteristics of genetic prion disease in a young man carrying the PRNP-G114V variant. METHODS: We performed genetic, histologic, and molecular studies, combined with in vivo transmission studies and in vitro replication st...

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Detalles Bibliográficos
Autores principales: Cali, Ignazio, Mikhail, Fadi, Qin, Kefeng, Gregory, Crystal, Solanki, Ani, Martinez, Manuel Camacho, Zhao, Lili, Appleby, Brian, Gambetti, Pierluigi, Norstrom, Eric, Mastrianni, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089695/
https://www.ncbi.nlm.nih.gov/pubmed/30109268
http://dx.doi.org/10.1212/NXG.0000000000000253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089695/
https://www.ncbi.nlm.nih.gov/pubmed/30109268
http://dx.doi.org/10.1212/NXG.0000000000000253

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