Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunate-induced apoptosis

The present study assessed the antitumor effect of artesunate (ART) in vitro and in vivo, as well as its underlying mechanism of action in HCT116 colon cancer cells. An MTT assay, DAPI staining, flow cytometry, western blotting, immunohistochemistry, transmission electron microscopy and TUNEL assay...

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Detalles Bibliográficos
Autores principales: Jiang, Feng, Zhou, Jin-Yong, Zhang, Dan, Liu, Ming-Hao, Chen, Yu-Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089754/
https://www.ncbi.nlm.nih.gov/pubmed/29901098
http://dx.doi.org/10.3892/ijmm.2018.3712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089754/
https://www.ncbi.nlm.nih.gov/pubmed/29901098
http://dx.doi.org/10.3892/ijmm.2018.3712

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