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Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunate-induced apoptosis
The present study assessed the antitumor effect of artesunate (ART) in vitro and in vivo, as well as its underlying mechanism of action in HCT116 colon cancer cells. An MTT assay, DAPI staining, flow cytometry, western blotting, immunohistochemistry, transmission electron microscopy and TUNEL assay...
Autores principales: | Jiang, Feng, Zhou, Jin-Yong, Zhang, Dan, Liu, Ming-Hao, Chen, Yu-Gen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089754/ https://www.ncbi.nlm.nih.gov/pubmed/29901098 http://dx.doi.org/10.3892/ijmm.2018.3712 |
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