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Fasudil preserves lung endothelial function and reduces pulmonary vascular remodeling in a rat model of end-stage pulmonary hypertension with left heart disease

Pulmonary hypertension (PH) due to left heart disease (LHD) is a common condition associated with significant morbidity. It contributes to the elevation of pulmonary vascular resistance and mean pulmonary pressure, eventually leading to heart failure and even mortality. The present study aimed to ex...

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Detalles Bibliográficos
Autores principales: Zhuang, Rulin, Wu, Jinfu, Lin, Fang, Han, Lu, Liang, Xiaoting, Meng, Qingshu, Jiang, Yuyu, Wang, Zhulin, Yue, Aixue, Gu, Yuying, Fan, Huimin, Zhou, Xiaohui, Liu, Zhongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089763/
https://www.ncbi.nlm.nih.gov/pubmed/29901088
http://dx.doi.org/10.3892/ijmm.2018.3728