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Hypoxia-induced expression of CXCR4 favors trophoblast cell migration and invasion via the activation of HIF-1α
The placenta initially develops in a low-oxygen environment up to week 8–10 of gestation, and a low oxygen level is a critical factor in the regulation of trophoblast migration and invasion. CXC chemokine receptor 4 (CXCR4) is transcriptionally activated by hypoxia in cancer cells. However, whether...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089771/ https://www.ncbi.nlm.nih.gov/pubmed/29786753 http://dx.doi.org/10.3892/ijmm.2018.3701 |