Cargando…

Hypoxia-induced expression of CXCR4 favors trophoblast cell migration and invasion via the activation of HIF-1α

The placenta initially develops in a low-oxygen environment up to week 8–10 of gestation, and a low oxygen level is a critical factor in the regulation of trophoblast migration and invasion. CXC chemokine receptor 4 (CXCR4) is transcriptionally activated by hypoxia in cancer cells. However, whether...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Zhan, Li, Pengyun, Wang, Yan, Yan, Huan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089771/ https://www.ncbi.nlm.nih.gov/pubmed/29786753 http://dx.doi.org/10.3892/ijmm.2018.3701

Ejemplares similares

Hypoxia Promotes Migration and Induces CXCR4 Expression via HIF-1α Activation in Human Osteosarcoma
por: Guo, Mingjun, et al.
Publicado: (2014)

Hypoxia-induced TET1 facilitates trophoblast cell migration and invasion through HIF1α signaling pathway
por: Zhu, Jingping, et al.
Publicado: (2017)

HIF-2α, but not HIF-1α, mediates hypoxia-induced up-regulation of Flt-1 gene expression in placental trophoblasts
por: Sasagawa, Tadashi, et al.
Publicado: (2018)

Icariin promotes the migration of bone marrow stromal cells via the SDF-1α/HIF-1α/CXCR4 pathway
por: Zhu, Haiyan, et al.
Publicado: (2018)

Effects of hypoxia inducible factors-1α on autophagy and invasion of trophoblasts
por: Choi, Jong-Ho, et al.
Publicado: (2012)

Hypoxia-induced HIF-1α promotes Listeria monocytogenes invasion into tilapia
por: Wang, Jing, et al.
Publicado: (2023)

TCDD Induces the Hypoxia-Inducible Factor (HIF)-1α Regulatory Pathway in Human Trophoblastic JAR Cells
por: Liao, Tien-Ling, et al.
Publicado: (2014)

Modulatory effects of trophoblast-secreted CXCL12 on the migration and invasion of human first-trimester decidual epithelial cells are mediated by CXCR4 rather than CXCR7
por: Zheng, Jiayi, et al.
Publicado: (2018)

Clinicopathologic Significance of HIF-1α, CXCR4, and VEGF Expression in Colon Cancer
por: Wu, Yugang, et al.
Publicado: (2010)

Autophagy Induced by HIF1α Overexpression Supports Trophoblast Invasion by Supplying Cellular Energy
por: Yamanaka-Tatematsu, Mikiko, et al.
Publicado: (2013)

IGF-1R Promotes Symmetric Self-Renewal and Migration of Alkaline Phosphatase(+) Germ Stem Cells through HIF-2α-OCT4/CXCR4 Loop under Hypoxia
por: Kuo, Yung-Che, et al.
Publicado: (2018)

Hypoxia-inducible factor 1α (HIF-1α) and reactive oxygen species (ROS) mediates radiation-induced invasiveness through the SDF-1α/CXCR4 pathway in non-small cell lung carcinoma cells
por: Gu, Qing, et al.
Publicado: (2015)

Hypoxia promotes the migration and invasion of human hepatocarcinoma cells through the HIF-1α–IL-8–Akt axis
por: Fei, Maoyun, et al.
Publicado: (2018)

FtMt reduces oxidative stress-induced trophoblast cell dysfunction via the HIF-1α/VEGF signaling pathway
por: Xu, Xia, et al.
Publicado: (2023)

Houshiheisan promotes angiogenesis via HIF-1α/VEGF and SDF-1/CXCR4 pathways: in vivo and in vitro
por: Xiang, Yangyang, et al.
Publicado: (2019)

CXCR7 is induced by hypoxia and mediates glioma cell migration towards SDF-1α
por: Esencay, Mine, et al.
Publicado: (2013)

HIF-1α affects trophoblastic apoptosis involved in the onset of preeclampsia by regulating FOXO3a under hypoxic conditions
por: Zhang, Zhan, et al.
Publicado: (2020)

Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
por: Bao, Lei, et al.
Publicado: (2018)

Metformin suppresses hypoxia-induced migration via the HIF-1α/VEGF pathway in gallbladder cancer in vitro and in vivo
por: Ye, Jianwen, et al.
Publicado: (2019)

PDGF-BB is involved in HIF-1α/CXCR4/CXCR7 axis promoting capillarization of hepatic sinusoidal endothelial cells
por: Fang, Jing, et al.
Publicado: (2022)

Placental homing peptide guides HIF1α‑silenced exosomes conjugates for targeted enhancement of invasion of trophoblast cells
por: Chen, Fangrong, et al.
Publicado: (2023)

Suppression of TRPM7 Inhibited Hypoxia-Induced Migration and Invasion of Androgen-Independent Prostate Cancer Cells by Enhancing RACK1-Mediated Degradation of HIF-1α
por: Yang, Fei, et al.
Publicado: (2020)

Interleukin-17 promotes proliferation, migration, and invasion of trophoblasts via regulating PPAR-γ/RXR-α/Wnt signaling
por: Zhang, Zhuo, et al.
Publicado: (2022)

Hypoxia favors myosin heavy chain beta gene expression in an Hif-1alpha-dependent manner
por: Binó, Lucia, et al.
Publicado: (2017)

CXCR4 is a prognostic marker that inhibits the invasion and migration of gastric cancer by regulating VEGF expression
por: Chen, Gaoyang, et al.
Publicado: (2021)

Follistatin Is a Novel Chemoattractant for Migration and Invasion of Placental Trophoblasts of Mice
por: Li, Jing, et al.
Publicado: (2022)

Exogenous SDF-1α Protects Human Myocardium from Hypoxia-Reoxygenation Injury via CXCR4
por: Malik, A., et al.
Publicado: (2015)

MiR-326 inhibits trophoblast growth, migration, and invasion by targeting PAX8 via Hippo pathway
por: Zang, Junjie, et al.
Publicado: (2022)

Hypoxia stimulates the expression of macrophage migration inhibitory factor in human vascular smooth muscle cells via HIF-1α dependent pathway
por: Fu, Hua, et al.
Publicado: (2010)

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
por: Mole, David R., et al.
Publicado: (2009)

Association of Age with the Expression of Hypoxia-Inducible Factors HIF-1α, HIF-2α, HIF-3α and VEGF in Lung and Heart of Tibetan Sheep
por: He, Yanyu, et al.
Publicado: (2019)

Calpain‐1 mediates vascular remodelling and fibrosis via HIF‐1α in hypoxia‐induced pulmonary hypertension
por: Deng, Haiyan, et al.
Publicado: (2022)

Altered expression of ADM and ADM2 by hypoxia regulates migration of trophoblast and HLA-G expression
por: Gu, Changdai, et al.
Publicado: (2020)

Bradykinin promotes migration and invasion of human immortalized trophoblasts
por: Erices, Rafaela, et al.
Publicado: (2011)

Effects of estradiol on HIF-1α expression and trophoblast differentiation in first trimester villous explant cultures
por: Cho, Geum Joon, et al.
Publicado: (2018)

Trophoblast-Specific Expression of Hif-1α Results in Preeclampsia-Like Symptoms and Fetal Growth Restriction
por: Albers, Renee E., et al.
Publicado: (2019)

HIF2α Upregulates the Migration Factor ODZ1 under Hypoxia in Glioblastoma Stem Cells
por: Carcelén, María, et al.
Publicado: (2022)

The Role of SDF-1α-CXCR4/CXCR7 in Migration of Human Periodontal Ligament Stem Cells
por: Xu, Jialei, et al.
Publicado: (2023)

SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis
por: Uygur, Berna, et al.
Publicado: (2011)

Beluga whale pVHL enhances HIF-2α activity via inducing HIF-2α proteasomal degradation under hypoxia
por: Bi, Jianling, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_mdfnn50nslat9qcjgbrlaanb0k