Cargando…

IL-1β and TNF-α suppress TGF-β-promoted NGF expression in periodontal ligament-derived fibroblasts through inactivation of TGF-β-induced Smad2/3- and p38 MAPK-mediated signals

Mechanosensitive (MS) neurons in the periodontal ligament (PDL) pass information to the trigeminal ganglion when excited by mechanical stimulation of the tooth. During occlusal tooth trauma of PDL tissues, MS neurons are injured, resulting in atrophic neurites and eventual degeneration of MS neurons...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ohta, Maiko, Chosa, Naoyuki, Kyakumoto, Seiko, Yokota, Seiji, Okubo, Naoto, Nemoto, Akira, Kamo, Masaharu, Joh, Shigeharu, Satoh, Kenichi, Ishisaki, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089780/ https://www.ncbi.nlm.nih.gov/pubmed/29901090 http://dx.doi.org/10.3892/ijmm_2018.3714

Ejemplares similares

TGF-β-Operated Growth Inhibition and Translineage Commitment into Smooth Muscle Cells of Periodontal Ligament-Derived Endothelial Progenitor Cells through Smad- and p38 MAPK-Dependent Signals
por: Yoshida, Mariko, et al.
Publicado: (2012)

Water-soluble factors eluated from surface pre-reacted glass-ionomer filler promote osteoblastic differentiation of human mesenchymal stem cells
por: Nemoto, Akira, et al.
Publicado: (2018)

PDGF-induced PI3K-mediated signaling enhances the TGF-β-induced osteogenic differentiation of human mesenchymal stem cells in a TGF-β-activated MEK-dependent manner
por: YOKOTA, JUN, et al.
Publicado: (2014)

Zoledronic acid suppresses transforming growth factor-β-induced fibrogenesis by human gingival fibroblasts
por: KOMATSU, YUKO, et al.
Publicado: (2016)

ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint
por: Yokota, Seiji, et al.
Publicado: (2017)

Receptor tyrosine kinase ligands and inflammatory cytokines cooperatively suppress the fibrogenic activity in temporomandibular-joint-derived fibroblast-like synoviocytes via mitogen-activated protein kinase kinase/extracellular signal-regulated kinase
por: Matsumoto, Shikino, et al.
Publicado: (2020)

Transforming growth factor-β1 suppresses bone morphogenetic protein-2-induced mesenchymal-epithelial transition in HSC-4 human oral squamous cell carcinoma cells via Smad1/5/9 pathway suppression
por: Chiba, Takahiro, et al.
Publicado: (2017)

Cell–cell interactions between monocytes/macrophages and synoviocyte-like cells promote inflammatory cell infiltration mediated by augmentation of MCP-1 production in temporomandibular joint
por: Ibi, Miho, et al.
Publicado: (2018)

VEGF-C and TGF-β reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes
por: IGARASHI, YASUYUKI, et al.
Publicado: (2016)

TGF-β1 induces N-cadherin expression by upregulating Sox9 expression and promoting its nuclear translocation in human oral squamous cell carcinoma cells
por: Hirano, Taifu, et al.
Publicado: (2020)

TGF-β and TGF-β/Smad Signaling in the Interactions between Echinococcus multilocularis and Its Hosts
por: Wang, Junhua, et al.
Publicado: (2013)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

Smad4-mediated TGF-β signaling in tumorigenesis
por: Yang, Guan, et al.
Publicado: (2010)

The regulation of TGF-β/SMAD signaling by protein deubiquitination
por: Zhang, Juan, et al.
Publicado: (2014)

The role of TGF-β/SMAD4 signaling in cancer
por: Zhao, Ming, et al.
Publicado: (2018)

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis
por: Yu, Xiao-Yong, et al.
Publicado: (2022)

Extracellular adenosine 5ʹ-diphosphate promotes MCP-1/CCL2 expression via the P2Y(13) purinergic receptor/ERK signaling axis in temporomandibular joint-derived mouse fibroblast-like synoviocytes
por: Yokota, Seiji, et al.
Publicado: (2022)

Interfering with TGFβ-induced Smad3 nuclear accumulation differentially affects TGFβ-dependent gene expression
por: Lindemann, Ralph K, et al.
Publicado: (2003)

Inhibition of Wilms' Tumor Proliferation and Invasion by Blocking TGF-β Receptor I in the TGF-β/Smad Signaling Pathway
por: Shi, Qinlin, et al.
Publicado: (2020)

Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation
por: Lan, Hui Yao
Publicado: (2011)

Roles of TGFβ signaling Smads in squamous cell carcinoma
por: Han, Gangwen, et al.
Publicado: (2011)

Non-degradative ubiquitination in Smad-dependent TGF-β signaling
por: Tang, Liu-Ya, et al.
Publicado: (2011)

Regulation of TGF-β Superfamily Signaling by SMAD Mono-Ubiquitination
por: Xie, Feng, et al.
Publicado: (2014)

Rejuvenation by inhibiting TGF-β1/pSmad signaling
por: Corder, Elizabeth H., et al.
Publicado: (2015)

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis
por: Walton, Kelly L., et al.
Publicado: (2017)

TGF-β/Smad Signalling in Neurogenesis: Implications for Neuropsychiatric Diseases
por: Hiew, Lih-Fhung, et al.
Publicado: (2021)

Protection from β-cell apoptosis by inhibition of TGF-β/Smad3 signaling
por: Lee, Ji-Hyeon, et al.
Publicado: (2020)

Immunohistochemical Expression of TGF-Β1, SMAD4, SMAD7, TGFβRII and CD68-Positive TAM Densities in Papillary Thyroid Cancer
por: Ivanova, Koni, et al.
Publicado: (2018)

MicroRNA-133b targets TGFβ receptor I to inhibit TGF-β-induced epithelial-to-mesenchymal transition and metastasis by suppressing the TGF-β/SMAD pathway in breast cancer
por: WANG, SHENGJIE, et al.
Publicado: (2019)

TGF-β Signaling in Lung Health and Disease
por: Saito, Akira, et al.
Publicado: (2018)

TGF-β receptor inhibitor LY2109761 enhances the radiosensitivity of gastric cancer by inactivating the TGF-β/SMAD4 signaling pathway
por: Yang, Tian, et al.
Publicado: (2019)

Berberine Suppresses EMT in Liver and Gastric Carcinoma Cells through Combination with TGFβR Regulating TGF-β/Smad Pathway
por: Du, Haiyan, et al.
Publicado: (2021)

SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4
por: Bertrand-Chapel, Adrien, et al.
Publicado: (2022)

[Corrigendum] MicroRNA-133b targets TGFβ receptor I to inhibit TGF-β-induced epithelial-to-mesenchymal transition and metastasis by suppressing the TGF-β/SMAD pathway in breast cancer
por: Wang, Shengjie, et al.
Publicado: (2023)

TGFβ-mediated expression of TGFβ-activating integrins in SSc monocytes: disturbed activation of latent TGFβ?
por: van Caam, A., et al.
Publicado: (2020)

Msk is required for nuclear import of TGF-β/BMP-activated Smads
por: Xu, Lan, et al.
Publicado: (2007)

Roles of Autocrine TGF-β Receptor and Smad Signaling in Adipocyte Differentiation
por: Choy, Lisa, et al.
Publicado: (2000)

TGF-β/Smad signaling during hepatic fibro-carcinogenesis (Review)
por: YOSHIDA, KATSUNORI, et al.
Publicado: (2014)

An inhibitory role of NEK6 in TGFβ/Smad signaling pathway
por: Zuo, Jie, et al.
Publicado: (2015)

TGF-β induces Smad2 Phosphorylation, ARE Induction, and Trophoblast Differentiation
por: Albers, Renee E., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qu8cl2cjk1av5hth6tesr9m77u