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Targeting an oncogenic kinase/phosphatase signaling network for cancer therapy

Protein kinases and phosphatases signal by phosphorylation and dephosphorylation to precisely control the activities of their individual and common substrates for a coordinated cellular outcome. In many situations, a kinase/phosphatase complex signals dynamically in time and space through their reci...

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Detalles Bibliográficos
Autores principales: Qi, Xiao-Mei, Wang, Fang, Mortensen, Matthew, Wertz, Ryan, Chen, Guan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089844/
https://www.ncbi.nlm.nih.gov/pubmed/30109176
http://dx.doi.org/10.1016/j.apsb.2018.05.007