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Targeting an oncogenic kinase/phosphatase signaling network for cancer therapy
Protein kinases and phosphatases signal by phosphorylation and dephosphorylation to precisely control the activities of their individual and common substrates for a coordinated cellular outcome. In many situations, a kinase/phosphatase complex signals dynamically in time and space through their reci...
Autores principales: | Qi, Xiao-Mei, Wang, Fang, Mortensen, Matthew, Wertz, Ryan, Chen, Guan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089844/ https://www.ncbi.nlm.nih.gov/pubmed/30109176 http://dx.doi.org/10.1016/j.apsb.2018.05.007 |
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