Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy

The mitogen-activated protein kinases (MAPK) pathway, often known as the RAS-RAF-MEK-ERK signal cascade, functions to transmit upstream signals to its downstream effectors to regulate physiological process such as cell proliferation, differentiation, survival and death. As the most frequently mutate...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Feifei, Yang, Xiaotong, Geng, Meiyu, Huang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089851/
https://www.ncbi.nlm.nih.gov/pubmed/30109180
http://dx.doi.org/10.1016/j.apsb.2018.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089851/
https://www.ncbi.nlm.nih.gov/pubmed/30109180
http://dx.doi.org/10.1016/j.apsb.2018.01.008

Ejemplares similares