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A multi-state model of chemoresistance to characterize phenotypic dynamics in breast cancer
The development of resistance to chemotherapy is a major cause of treatment failure in breast cancer. While mathematical models describing the dynamics of resistant cancer cell subpopulations have been proposed, experimental validation has been difficult due to the complex nature of resistance that...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089904/ https://www.ncbi.nlm.nih.gov/pubmed/30104569 http://dx.doi.org/10.1038/s41598-018-30467-w |