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Highly efficient capture of cancer cells expressing EGFR by microfluidic methods based on antigen-antibody association

Epidermal growth factor receptor (EGFR) was evaluated as a target antigen for cancer cell capture by microfluidic methods based on antigen-antibody association. A polymer CTC-chip microfluidic device was surface-functionalized with three different anti-EGFR antibodies and used to capture EGFR-expres...

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Detalles Bibliográficos
Autores principales: Ohnaga, Takashi, Takei, Yoshinori, Nagata, Takuya, Shimada, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089922/
https://www.ncbi.nlm.nih.gov/pubmed/30104638
http://dx.doi.org/10.1038/s41598-018-30511-9