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In situ transcriptome characteristics are lost following culture adaptation of adult cardiac stem cells

Regenerative therapeutic approaches for myocardial diseases often involve delivery of stem cells expanded ex vivo. Prior studies indicate that cell culture conditions affect functional and phenotypic characteristics, but relationship(s) of cultured cells derived from freshly isolated populations and...

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Detalles Bibliográficos
Autores principales: Kim, Taeyong, Echeagaray, Oscar H., Wang, Bingyan J., Casillas, Alexandria, Broughton, Kathleen M., Kim, Bong-Hyun, Sussman, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089936/
https://www.ncbi.nlm.nih.gov/pubmed/30104715
http://dx.doi.org/10.1038/s41598-018-30551-1