R-spondin-2 is a Wnt agonist that regulates osteoblast activity and bone mass

The R-spondin family of proteins are Wnt agonists, and the complete embryonic disruption of Rspo2 results in skeletal developmental defects that recapitulate the phenotype observed with Lrp5/6 deficiency. Previous work has shown that R-spondin-2 (Rspo2, RSPO2) is both highly expressed in Wnt-stimula...

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Detalles Bibliográficos
Autores principales: Knight, M. Noelle, Karuppaiah, Kannan, Lowe, Michele, Mohanty, Sarthak, Zondervan, Robert L., Bell, Sheila, Ahn, Jaimo, Hankenson, Kurt D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089978/
https://www.ncbi.nlm.nih.gov/pubmed/30131881
http://dx.doi.org/10.1038/s41413-018-0026-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089978/
https://www.ncbi.nlm.nih.gov/pubmed/30131881
http://dx.doi.org/10.1038/s41413-018-0026-7

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