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Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure

The energy metabolism of the failing heart is characterized by reduced fatty acid (FA) oxidation and an increase in glucose utilization. However, little is known about how energy metabolism-function relationship is relevant to pathophysiology of heart failure. Recent study showed that the genetic de...

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Detalles Bibliográficos
Autores principales: Umbarawan, Yogi, Syamsunarno, Mas Rizky A. A., Koitabashi, Norimichi, Obinata, Hideru, Yamaguchi, Aiko, Hanaoka, Hirofumi, Hishiki, Takako, Hayakawa, Noriyo, Sano, Motoaki, Sunaga, Hiroaki, Matsui, Hiroki, Tsushima, Yoshito, Suematsu, Makoto, Kurabayashi, Masahiko, Iso, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089997/
https://www.ncbi.nlm.nih.gov/pubmed/30104639
http://dx.doi.org/10.1038/s41598-018-30616-1