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Protective Effect of Celecoxib on Early Postoperative Cognitive Dysfunction in Geriatric Patients

Objective: Inflammation plays a key role in the etiology and pathology of postoperative cognitive dysfunction (POCD). Cyclooxygenase (COX)-2 inhibitor celecoxib is used for the treatment of acute pain due to its potent anti-inflammatory and analgesic effects. Herein, we evaluated the effects of cele...

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Detalles Bibliográficos
Autores principales: Zhu, Yangzi, Yao, Rui, Li, Yan, Wu, Congyou, Heng, Lei, Zhou, Meiyan, Yan, Li, Deng, Yan, Zhang, Zhe, Ping, Lei, Wu, Yuqing, Wang, Shengtao, Wang, Liwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090028/
https://www.ncbi.nlm.nih.gov/pubmed/30131758
http://dx.doi.org/10.3389/fneur.2018.00633