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Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups

Acyltransferase domains (ATs) of polyketide synthases (PKSs) are critical for loading of acyl groups on acyl carrier protein domains (A) via self- and trans-acylation reactions, to produce structurally diverse polyketides. However, the interaction specificity between ATs and unusual acyl units is ra...

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Detalles Bibliográficos
Autores principales: Shen, Jie-Jie, Chen, Fu, Wang, Xiao-Xuan, Liu, Xiao-Fang, Chen, Xin-Ai, Mao, Xu-Ming, Li, Yong-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090053/
https://www.ncbi.nlm.nih.gov/pubmed/30131798
http://dx.doi.org/10.3389/fmicb.2018.01840