Cargando…
Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups
Acyltransferase domains (ATs) of polyketide synthases (PKSs) are critical for loading of acyl groups on acyl carrier protein domains (A) via self- and trans-acylation reactions, to produce structurally diverse polyketides. However, the interaction specificity between ATs and unusual acyl units is ra...
Autores principales: | Shen, Jie-Jie, Chen, Fu, Wang, Xiao-Xuan, Liu, Xiao-Fang, Chen, Xin-Ai, Mao, Xu-Ming, Li, Yong-Quan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090053/ https://www.ncbi.nlm.nih.gov/pubmed/30131798 http://dx.doi.org/10.3389/fmicb.2018.01840 |
Ejemplares similares
-
Overexpression of Two New Acyl-CoA:Diacylglycerol Acyltransferase 2-Like Acyl-CoA:Sterol Acyltransferases Enhanced Squalene Accumulation in Aurantiochytrium limacinum
por: Rau, E-Ming, et al.
Publicado: (2022) -
In vitro reconstitution of substrate S-acylation by the zDHHC family of protein acyltransferases
por: Elliot Murphy, R., et al.
Publicado: (2022) -
Engineering the acyltransferase domain of epothilone polyketide synthase to alter the substrate specificity
por: Wang, Huimin, et al.
Publicado: (2021) -
A novel fold for acyltransferase-3 (AT3) proteins provides a framework for transmembrane acyl-group transfer
por: Newman, Kahlan E, et al.
Publicado: (2023) -
A Polyketide Synthase Acyltransferase Domain Structure Suggests a Recognition Mechanism for Its Hydroxymalonyl-Acyl Carrier Protein Substrate
por: Park, Hyunjun, et al.
Publicado: (2014)