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Therapeutic Application of Bacteriophage PHB02 and Its Putative Depolymerase Against Pasteurella multocida Capsular Type A in Mice

Phage PHB02 specifically infects Pasteurella multocida capsular serogroup A strains. In this study, we found that capsule deletion mutants were not lysed by PHB02, suggesting that the capsule of P. multocida serogroup A strains might be the primary receptor. Based on sequence analysis, a gene encodi...

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Detalles Bibliográficos
Autores principales: Chen, Yibao, Sun, Erchao, Yang, Lan, Song, Jiaoyang, Wu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090149/
https://www.ncbi.nlm.nih.gov/pubmed/30131774
http://dx.doi.org/10.3389/fmicb.2018.01678