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No Effect of Dose Adjustment to the CYP2D6 Genotype in Patients With Severe Mental Illness

Background: The CYP2D6 enzyme is involved in the metabolism of numerous psychopharmacological drugs. Guidelines recommend how to adjust the dose of medication based on the CYP2D6 genotype. Aims: To evaluate the effect of dose adjustment to the CYP2D6 genotype and phenotype, in patients with severe m...

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Detalles Bibliográficos
Autores principales: Koopmans, Anne B., Vinkers, David J., Poulina, Igmar T., Gelan, Petra J. A., van Schaik, Ron H. N., Hoek, Hans W., van Harten, Peter N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090167/
https://www.ncbi.nlm.nih.gov/pubmed/30131727
http://dx.doi.org/10.3389/fpsyt.2018.00349