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No Effect of Dose Adjustment to the CYP2D6 Genotype in Patients With Severe Mental Illness
Background: The CYP2D6 enzyme is involved in the metabolism of numerous psychopharmacological drugs. Guidelines recommend how to adjust the dose of medication based on the CYP2D6 genotype. Aims: To evaluate the effect of dose adjustment to the CYP2D6 genotype and phenotype, in patients with severe m...
Autores principales: | Koopmans, Anne B., Vinkers, David J., Poulina, Igmar T., Gelan, Petra J. A., van Schaik, Ron H. N., Hoek, Hans W., van Harten, Peter N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090167/ https://www.ncbi.nlm.nih.gov/pubmed/30131727 http://dx.doi.org/10.3389/fpsyt.2018.00349 |
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