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Analysis of FK506-mediated functional recovery and neuroprotection in a rat model of spinal cord injury indicates that EGF is modulated in astrocytes

The present study aimed to evaluate whether the application of tacrolimus (FK506) could improve functional recovery in spinal cord injury (SCI) rat models by activating astrocytes, and to further investigate the underlying mechanisms of this action. Male Sprague-Dawley rats (n=56) were used to estab...

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Detalles Bibliográficos
Autores principales: Cai, Jun, Sun, Yu, Yin, Zaoyang, Wang, Daode, Shi, Kun, Fu, Yuxuan, Cao, Xiaojian, Ge, Yingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090233/
https://www.ncbi.nlm.nih.gov/pubmed/30116308
http://dx.doi.org/10.3892/etm.2018.6283