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Changes in osteogenic gene expression in hypertrophic chondrocytes induced by SIN-1

The molecular mechanisms underlying osteoarthritis (OA) and Kashin-Beck disease (KBD) remain poorly understood. Hypertrophic chondrocytes serve an important role in the development of both OA and KBD, whereas oxidative stress can contribute to the pathological progression of cartilage damage. Theref...

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Detalles Bibliográficos
Autores principales: He, Ying, Yao, Wen, Zhang, Meng, Zhang, Ying, Zhang, Dan, Jiang, Zhuocheng, Ma, Tianyou, Sun, Jian, Shao, Mingming, Chen, Jinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090273/
https://www.ncbi.nlm.nih.gov/pubmed/30116317
http://dx.doi.org/10.3892/etm.2018.6261