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Glycogenolysis in Acquired Glioma Resistance to Temozolomide: A Role for the [Ca(2+)](i)-dependent Activation of Na,K-ATPase/ERK(1/2) Signaling
Understanding the mechanistic basis for temozolomide (TMZ)-induced glioma resistance is an important obstacle in developing an effective form of chemotherapy for this type of tumor. Glycogenolysis is known to play an essential role in cellular proliferation and potassium homeostasis and involves the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090282/ https://www.ncbi.nlm.nih.gov/pubmed/30131700 http://dx.doi.org/10.3389/fphar.2018.00873 |