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Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer’s Disease

Alzheimer’s disease (AD) prevalence varies by sex, suggesting that sex chromosomes, sex hormones and/or their signaling could potentially modulate AD risk and progression. Low testosterone levels are reported in men with AD. Further, variation in the androgen receptor (AR) gene has been associated w...

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Detalles Bibliográficos
Autores principales: Carr, Jessie S., Bonham, Luke W., Morgans, Alicia K., Ryan, Charles J., Yokoyama, Jennifer S., Geier, Ethan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090298/
https://www.ncbi.nlm.nih.gov/pubmed/30131669
http://dx.doi.org/10.3389/fnins.2018.00529