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EphB2 Deficiency Induces Depression-Like Behaviors and Memory Impairment: Involvement of NMDA 2B Receptor Dependent Signaling

Receptor tyrosine kinase EphB2 mediates development of the neurogenic niche of excitatory neurons, suggesting the possibility that its inactivation plays a role in neuropsychiatric disorders including depression and memory impairment. While N-methyl-D-aspartate (NMDA) receptor is involved in regulat...

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Detalles Bibliográficos
Autores principales: Zhen, Linlin, Shao, Tuo, Luria, Victor, Li, Gaowen, Li, Zhi, Xu, Ying, Zhao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090375/
https://www.ncbi.nlm.nih.gov/pubmed/30131699
http://dx.doi.org/10.3389/fphar.2018.00862