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Revisiting Connectivity Map from a gene co-expression network analysis

The Connectivity Map (CMap) is a tool that has been extensively utilized to study drug repositioning and side-effect prediction. However, most of these analyses rely on signature genes, ignoring the pathways by which those genes are regulated, as well as the functional overlap of redundant genes. Th...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Tu, Wei, Li, Li, Liu, Yingfu, Wang, Shaobo, Li, Ling, Tao, Huan, He, Huaqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090433/
https://www.ncbi.nlm.nih.gov/pubmed/30112021
http://dx.doi.org/10.3892/etm.2018.6275